DAU was created as a result of the critical necessity, identified in high-level studies and legislation, for providing the Department of Defense Acquisition, Technology and Logistics workforce with a professional career path and consistency of training content and opportunity.

The Department of Defense issued DoD Directive 5000.57 in October 1991 which served as the University’s charter. Originally a loose consortium of existing training commands, DAU worked to standardize the training courses and establish mechanisms that that allowed for centralized equitable management of training funds for the DoD (AT&L) workforce.

In the late 1990s, the consortium arrangement was replaced with a centralized structure that operated more like a corporate university with a focus on case-based instruction and emphasizes the use of distance learning, mission assistance and knowledge sharing. The new structure also centralizes course development under the DAU headquarters.

On February 8, 2006, the Under Secretary of Defense for Acquisition, Technology and Logistics issued DoD Instruction 5000.57 which supersedes DoD Directive 5000.57. This new instruction describes the mission, responsibilities, functions, and authorities of DAU.